Validity of Elastography in Differentiating Benign and Malignant Thyroid Nodules, Keeping Histopathology as Gold Standard

Background: Elastography is a method recently being used in the evaluation of thyroid nodules by comparing tissue elasticity. The aim this study was to determine diagnostic accuracy elastography differentiation between benign and malignant nodules, taking histopathology as gold standard. Methods: Total 50 patients with palpable nodule any size age 20-60 years either gender were included. performed every patient using high resolution unit linear array probe centered at 7.5 MHz, consultant radiologist or noted. findings compared report Results: All subjected strain ultrasound elastography. USG supported diagnosis all patients. Histopathology confirmed 46 (true positive) cases where 4 (false had no lesion on histopathology. In negative patients, 47 true while 2 false negative. Overall sensitivity, specificity, positive predictive value, value standard 90.0%, 90.30%, 92.31%, 94.77% 93.18% respectively Conclusion: According study, non-invasive modality choice diagnosing nodules. Keywords: Thyroid cancer, Ultrasound elastography, Sensitivity, Specificity